Profound local hypothermia for myocardial protection during open-heart surgery
نویسندگان
چکیده
منابع مشابه
Open Cardiac Surgery during Profound Hypothermia
On Tuesday, 31st January 1961, I was privileged to assist at an operation performed y Mr. Ronald Belsey at the Bristol Royal Infirmary, for closure of an atrial septal e?t (A.S.D.) under profound hypothermia. This was the first case to be allotted 0 a student dresser, although the sixth one in the profound hypothermia series in r^stol, and an account of it may be of both topical and historical ...
متن کاملOpen Heart Surgery under Hypothermia
Fourty-three operations were performed on a total of 41 patients consisting of atrial septal defect, ventricular septal defect, ventricular septal defect with pulmonary stenosis, tetralogy of Fallot, aortic valve stenosis, pulmonary valve stenosis and coarctation of the aorta under hypothermia using intrathoracic rewarming. All patients but 2 cases with tetralogy Fallot have been completely cur...
متن کاملSurgery by direct vision in the open heart during hypothermia.
The heart for centuries was suspected of being a delicate organ; the slightest injury was said to be uniformly fatal. Both the great Billroth and Sir Stephen Paget decreed the organ to lie outside the domain of possible surgery. Yet in reality the heart is a compact muscular organ that, by virtue of highly specialized intrinsic properties, functions continuously throughout the lifetime of the i...
متن کاملAge-dependent and hypoxia-related differences in myocardial protection during pediatric open heart surgery.
BACKGROUND Current cardioplegic protection techniques used in pediatric cardiac surgery do not take into consideration age and cyanotic differences. The aim of the present work was to address this question by monitoring clinical outcome, myocardial metabolism, and reperfusion injury in pediatric patients protected by cold-crystalloid cardioplegia. METHODS AND RESULTS Fifty-eight patients (31 ...
متن کاملMechanisms of oxidative stress and myocardial protection during open-heart surgery
Cold heart protection via cardioplegia administration, limits the amount of oxygen demand. Systemic normothermia with warm cardioplegia was introduced due to the abundance of detrimental effects of hypothermia. A temperature of 32-33°C in combination with tepid blood cardioplegia of the same temperature appears to be protective enough for both; heart and brain. Reduction of nitric oxide (NO) co...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1973
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)40565-5